研究方向:
以模式植物拟南芥为材料,利用遗传学和分子生物学等技术解析蛋白质的生理功能及其作用机制。具体研究方向包括:
1. 酪蛋白激酶(Casein kinase 1)功能及作用机制
2. 表观遗传信号调控种子休眠与萌发的机理
科研项目:
1. 美高梅mgm1888网站人才引进启动基金,主持
2. 江苏省自然科学基金面上项目,主持
3. 江苏省双创博士人才项目,主持
4. 国家自然科学基金青年基金项目,主持
5. 广东省自然科学基金面上项目,主持
代表性论文: (#Co-first authors, *Corresponding authors)
1. Ruan J#, Chen H#, Zhu T#, Lei Y, Yuan L, Liu J, Wang Z, Kuang J, Lu W, Huang S and Li C*. 2021. Brassinosteroid represses the seed maturation program during the seed-to-seedling transition in Arabidopsis. Plant Physiology 186(1): 534-548.
2. Miao, W #., Dai, J #., Wang, Y., Wang, Q., Lu, C., La, Y., Niu, J., Tan, F., Zhou, S., Wu, Y., Chen, H*., La, H*. 2021. Roles of IDM3 and SDJ1/2/3 in Establishment and/or Maintenance of DNA Methylation in Arabidopsis. Plant Cell Physiology 62(9): 1409-1422.
3. Chen H, Tong J, Fu W, Liang Z, Xiao L, Yu Y, Xin S, Yuan L, Xiao L, Liu J, Cui Y, Huang S and Li C*. 2020. The H3K27me3 Demethylase RELATIVE OF EARLY FLOWERING6 Suppresses Seed Dormancy by Inducing Abscisic Acid Catabolism. Plant Physiology 184:1969-78.
4. Chen H#, Ruan J#, Chu P, Fu W, Liang Z, Li Y, Tong J, Xiao L, Liu J, Li C, and Huang S*. 2020. AtPER1 enhances primary seed dormancy and reduces seed germination by suppressing the ABA catabolism and GA biosynthesis in Arabidopsis seeds. The Plant Journal 101:310-23.
5. Chen H, Qu L, Xu Z, Zhu J, and Xue H*. 2018. EL1-like casein kinases suppress ABA signaling and responses by phosphorylating and destabilizing ABA receptors PYR/PYLs in Arabidopsis. Molecular Plant 11: 706-719.
6. Chen H #, Pu C#, Zhou Y, Ding Y, Li Y, Liu J, Jiang J, and Huang S*. 2016. Ectopic expression of NnPER1, a Nelumbo nucifera 1-cysteine peroxiredoxin antioxidant, enhances seed longevity and stress tolerance in Arabidopsis. The Plant Journal 88, 608-619.
7. Chen H, Chu P, Zhou Y, Li Y, Liu J, Ding Y, Tsang E, Jiang L, Wu K, Huang S*. 2012. Overexpression of AtOGG1, a DNA glycosylase/AP lyase, enhances seed longevity and abiotic stress tolerance in Arabidopsis. Journal of Experimental Botany 63, 4107-4121.
8. 陈虎辉,薛红卫。植物1型酪蛋白激酶的研究进展及展望。《生命科学》2018,30 (11): 1184-1192. (封面文章)
国家发明专利:
1. 黄上志,陈虎辉,拟南芥DNA糖苷酶AtOGG1在提高种子寿命和萌发活力中的应用,2013.10.16。
2. 黄上志,楚璞,陈虎辉,黎茵,周玉亮,一种莲膜联蛋白及其表达载体和应用,2013.2.20。
3. 黄上志,周玉亮,黎茵,楚璞,陈虎辉,莲金属硫蛋白基因MT2a在提高种子寿命和活力上的应用,2013.1.9。