男,理学博士,教授,博士生导师
联系方式:025-84396069; 电子邮箱:yifeng@njau.edu.cn; 地址:美高梅mgm1888网站生科楼C2006
实验室主页:https://xuyifeng.wixsite.com/xu-lab
本科毕业于美高梅mgm1888网站农学专业,硕士毕业于南京大学环境生物专业,2006年在新加坡国立大学生物系获得博士学位。2005年4月加入新加坡基因组研究中心从事博士后研究,2008年1月加入新加坡淡马锡生命研究所,2017年9月加入奈良先端科技大学院大学,2018年10月加入美高梅mgm1888网站生科院。2019年入选江苏特聘教授。
本人长期从事表观遗传与植物发育的相关研究,目前已经在主流期刊上发表18篇文章,其中第一作者(含共同一作)10篇,包括PNAS, Science, Nature Communications, Genes&Development, The EMBO Journal, Nucleic Acids Research等国际知名期刊。
一、研究方向:
课题组将以拟南芥,大豆和兰花等为研究材料,研究表观遗传调控开花时间,花序和花器官发育以及对环境因子(包括栽培技术)的适应性。研究将结合表观遗传组学、转录组学,代谢组学,利用高通量测序,染色体构象捕获,遗传学,生理生化,分子生物学等技术手段来解析表观遗传协调转录因子参与植物发育的分子机制,以及表观遗传在代际和代间的重编码规则。
课题组长期招收博士生和博士后(含师资博士后,欢迎对植物科学研究怀有热情的学生和年轻科研工作者加入团队。
二、招生方向:
硕士方向:
071001 植物学 05 (全日制)植物激素分子生物学; 09 (全日制)植物逆境生理与分子生物学
071008 发育生物学 02 (全日制)植物可塑性的表观遗传学; 04 (全日制)植物发育的分子机理
博士方向:
071001 植物学 新(全日制)植物表观遗传学;03 (全日制)植物逆境生理与分子生物学;
071008 发育生物学 01(全日制)植物发育的分子生物学;新(全日制)植物发育与表观遗传。
三、代表性研究论著
1. Yifeng Xu, Nobutoshi Yamaguchi, Eng-Seng Gan&Toshiro Ito. (2019) When to stop: an update on molecular mechanisms of floral meristem termination. J Exp Bot. 70(6):1711-1718.
2. Yifeng Xu, Nathanaël Prunet, Eng-Seng Gan, Yanbin Wang, Darragh Stewart, Frank Wellmer, Jiangbo Huang, Nobutoshi Yamaguchi, et al. (2018) SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis. EMBO J. 37 e97499.
3. Yifeng Xu, Eng-Seng Gan and Toshiro Ito. (2018) Detection of protein-protein interaction for plant transcription factors by the in situ proximity ligation assay In: Methods in Molecular Biology: Plant Transcription Factor. Springer.
4. Akira Uemura, Nobutoshi Yamaguchi, Yifeng Xu, et al. (2018) Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis. Plant Reproduction. 31(1): 89-105.
5. Nobutoshi Yamaguchi*, Jiangbo Huang*, Yifeng Xu, Keitaro Tanoi and Toshiro Ito. (2017) Fine-tuning of auxin homeostasis governs the transition from floral stem cell maintenance to gynoecium formation. Nature Communications. 8(1): 1125. (* 共同第一作者)
6. Eng-Seng Gan, Yifeng Xu and Toshiro Ito. (2015) Dynamics of H3K27me3 methylation and demethylation in plant development. Plant Signalling & Behaviour. 10(9):e1027851.
7. Siyi Guo, Bo Sun, Liang-Sheng Looi, Yifeng Xu, Eng-Seng Gan, Jiangbo Huang and Toshiro Ito. (2015) Co-ordination of Flower Development Through Epigenetic Regulation in Two Model Species: Rice and Arabidopsis. Plant & Cell Physiology. 56(5):830-842.
8. Yifeng Xu, Eng-Seng Gan, Jie Zhou, Wan-Yi Wee, Xiaoyu Zhang and Toshiro Ito. (2014) Arabidopsis MRG Domain Proteins Bridge Two Histone Modifications to Elevate Expression of Flowering Genes. Nucleic Acids Research. 42(17):10960-74.
9. Eng-Seng Gan, Yifeng Xu, Jie-Yun Wong, Jessamine Geraldine Goh, Bo Sun, Wanyi Wee, Jiangbo Huang and Toshiro Ito. (2014) Jumonji demethylases moderate precocious flowering at elevated temperature via regulation of FLC in Arabidopsis. Nature Communications. 30;5: 5098.
10. Fang Fang*, Yifeng Xu*, Kai-Khen Chew, Xi Chen, Huck Hui Ng, Paul Matsudaira. (2014) Coactivators p300/CBP maintain the identity of mouse embryonic stem cells by mediating long-range interactions. Stem Cells. 32(7):1805-16. (* 共同第一作者)
11. Bo Sun, Liang-Sheng Looi, Siyi Guo, Zemiao He, Eng-Seng Gan, Jiangbo Huang, Yifeng Xu, Wanyi Wee and Toshiro Ito. (2014) Timing mechanism dependent on cell division is invoked by Polycomb eviction in plant stem cells. Science. 343(6170): 1248559.
12. Yifeng Xu, Eng-Seng Gan, Toshiro Ito. (2014) Misexpression Approaches for the Manipulation of Flower Development. In: Flower Development: Methods and Protocols. Methods in Molecular Biology. ed. by José Luis Riechmann and Frank Wellmer, Springer.
13. Yifeng Xu, Eng-Seng Gan and Toshiro Ito. (2013) The AT-hook/PPC domain protein TEK negatively regulates floral repressors including MAF4 and MAF5. Plant Signalling & Behaviour. 8(8). e25006.
14. Yifeng Xu, Eng-Seng Gan, Toshiro Ito. (2013) Flowering and genome integrity control by a nuclear matrix protein in Arabidopsis. Nucleus. 4(4):274-276.
15. Yifeng Xu, Yizhong Wang, Hume Stroud, Xiaofeng Gu, Bo Sun, Eng-Seng Gan, Kian-Hong Ng, Steve Jacobsen, Yuehui He and Toshiro Ito. (2013) A Matrix Protein Silences Transposons and Repeats through Direct Interaction with Retinoblastoma-Associated Proteins. Current Biology. 23(4): 345-350.
16. Bo Sun, Yifeng Xu, Kian-Hong Ng and Toshiro Ito. (2009) A timing mechanism for stem cell maintenance and differentiation in Arabidopsis floral meristem. Genes & Development. 23(15): 1791-1804.
17. Hao Yu and Yifeng Xu. (2007) III.4 Orchids. In: Biotechnology in Agriculture and Forestry, Transgenic Crops VI, ed. By E.C. Pua and M.R. Davey, Springer-Verlag, Berlin Heidelberg, Germany.
18. Yifeng Xu, Lai Lai Teo, Jing Zhou, Prakash P. Kumar, Hao Yu. (2006) Floral organ identity genes in the orchid Dendrobium crumenatum. The Plant Journal. 46: 54-68.
19. Shuhua Yang, Hao Yu, Yifeng Xu, Chong Jing Goh. (2003) Investigation of cytokinin-deficient phenotypes in Arabidopsis by ectopic expression of orchid DSCKX1. FEBS Letters. 555(2):291-296.
20. Hao Yu, Yifeng Xu, Ee Ling Tan and Prakash P. Kumar. (2002) AGAMOUS-LIKE 24, a dosage-dependent mediator of the flowering signals. Proc Natl Acad Sci U. S. A. 99(25):16336-16341.